Motif ID: FOX{D1,D2}.p2

Z-value: 2.040


Transcription factors associated with FOX{D1,D2}.p2:

Gene SymbolEntrez IDGene Name
FOXD1 2297 forkhead box D1
FOXD2 2306 forkhead box D2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXD1chr5_-_72744351-0.465.1e-13Click!
FOXD2chr1_+_479016880.343.6e-07Click!


Activity profile for motif FOX{D1,D2}.p2.

activity profile for motif FOX{D1,D2}.p2


Sorted Z-values histogram for motif FOX{D1,D2}.p2

Sorted Z-values for motif FOX{D1,D2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{D1,D2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_145438437 44.627 NM_006472
TXNIP
thioredoxin interacting protein
chr5_-_42811959 43.006 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr12_-_9268440 40.125 A2M
alpha-2-macroglobulin
chr12_-_92539614 37.941 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr6_+_89791510 37.935 PNRC1
proline-rich nuclear receptor coactivator 1
chr12_-_9268513 37.260 A2M
alpha-2-macroglobulin
chrX_-_106960028 35.464 TSC22D3
TSC22 domain family, member 3
chr12_-_9268522 34.934 NM_000014
A2M
alpha-2-macroglobulin
chrX_-_106960268 33.880 NM_004089
TSC22D3
TSC22 domain family, member 3
chr22_-_31686707 33.479 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr12_-_9268475 28.611 A2M
alpha-2-macroglobulin
chr11_-_117747331 28.539 FXYD6
FXYD domain containing ion transport regulator 6
chr17_-_29641068 27.366 EVI2B
ecotropic viral integration site 2B
chr10_-_45474210 27.357 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr13_-_41240607 27.268 NM_002015
FOXO1
forkhead box O1
chr19_+_12902295 25.666 NM_002229
JUNB
jun B proto-oncogene
chr14_+_74551655 24.615 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr1_+_84630374 23.750 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_117297056 23.238 NM_001767
CD2
CD2 molecule
chr5_-_131132642 22.992 FNIP1
folliculin interacting protein 1
chr10_-_90750955 22.584 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr14_-_74551159 21.839 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr11_+_73359734 21.481 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr14_-_21493858 21.117 NDRG2
NDRG family member 2
chr5_-_169724614 20.937 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chrX_-_101112548 20.641 NM_032946
NXF5
nuclear RNA export factor 5
chr3_+_23987514 20.589 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr14_-_74551073 20.464 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_-_21493910 20.445 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr4_-_2263706 19.704 NM_006454
MXD4
MAX dimerization protein 4
chr6_+_122793061 19.678 NM_181794
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr22_-_31688329 19.404 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr14_+_24584009 18.851 DCAF11
DDB1 and CUL4 associated factor 11
chr1_-_92351613 18.176 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr11_-_5255712 17.279 NM_000519
HBD
hemoglobin, delta
chr12_-_91576805 17.106 NM_001920
DCN
decorin
chr10_+_99079017 17.086 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr17_-_29641094 17.018 NM_006495
EVI2B
ecotropic viral integration site 2B
chr17_-_29641087 16.959 EVI2B
ecotropic viral integration site 2B
chrX_+_70315637 16.958 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr14_-_24584125 16.884 NRL
neural retina leucine zipper
chr16_+_77233348 16.548 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr5_+_72251869 16.444


chr16_-_1832576 16.442 NM_080861
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr7_+_106809405 16.034 NM_001244262
NM_012257
HBP1

HMG-box transcription factor 1

chr5_-_169724782 16.005 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_227127993 15.857 ADCK3
aarF domain containing kinase 3
chr14_+_24584321 15.785 DCAF11
DDB1 and CUL4 associated factor 11
chr6_-_31550065 15.733 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr7_+_134832765 15.607 NM_018295
TMEM140
transmembrane protein 140
chr1_+_227127959 15.514 ADCK3
aarF domain containing kinase 3
chr17_+_58755158 15.150 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr17_-_66951381 14.971 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_+_106696508 14.956 NM_152772
TCP11L2
t-complex 11 (mouse)-like 2
chr16_+_30484049 14.934 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr7_-_140624280 14.903 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr18_-_53257033 14.848 NM_001243227
NM_001243228
TCF4

transcription factor 4

chr18_-_53303129 14.801 NM_001243226
TCF4
transcription factor 4
chr19_-_58609606 14.786 NM_001145543
NM_001145544
NM_023926
ZSCAN18


zinc finger and SCAN domain containing 18


chr22_-_38902344 14.681 NM_001098504
NM_006386
DDX17

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

chr19_-_58609574 14.397 ZSCAN18
zinc finger and SCAN domain containing 18
chr5_-_169724734 14.298 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr2_+_74120132 14.263 ACTG2
actin, gamma 2, smooth muscle, enteric
chr11_+_13299260 14.253 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr10_+_99400469 14.243 PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr11_-_65150107 14.242 NM_001077241
NM_182556
SLC25A45

solute carrier family 25, member 45

chr11_+_117049838 14.213 NM_001040455
SIDT2
SID1 transmembrane family, member 2
chr14_-_76447445 14.089 TGFB3
transforming growth factor, beta 3
chr14_-_91526912 14.046 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr1_+_227127999 14.039 ADCK3
aarF domain containing kinase 3
chr9_-_3525973 14.029 NM_002919
NM_134428
RFX3

regulatory factor X, 3 (influences HLA class II expression)

chr2_+_97481977 13.991 NM_017623
NM_199078
CNNM3

cyclin M3

chr5_-_169724817 13.930 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr14_-_76448091 13.877 NM_003239
TGFB3
transforming growth factor, beta 3
chr7_-_17980102 13.691 NM_015132
SNX13
sorting nexin 13
chr16_+_30483959 13.640 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr8_-_134309448 13.424 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr1_-_12677347 13.371 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr15_+_81589240 13.359 NM_004513
IL16
interleukin 16
chr16_-_1832571 13.359 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr12_-_91576579 13.322 DCN
decorin
chr19_+_50380681 13.224 NM_001168222
NM_024682
TBC1D17

TBC1 domain family, member 17

chr2_+_74120092 13.195 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr19_+_859658 13.160 NM_001928
CFD
complement factor D (adipsin)
chr11_+_13299391 13.110 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr10_+_111985628 12.923 NM_005962
MXI1
MAX interactor 1
chr14_+_24583979 12.862 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr1_+_227127937 12.847 NM_020247
ADCK3
aarF domain containing kinase 3
chr14_-_75518132 12.788 NM_001040108
NM_014381
MLH3

mutL homolog 3 (E. coli)

chr9_-_135819995 12.762 NM_000368
NM_001162426
NM_001162427
TSC1


tuberous sclerosis 1


chr11_+_13299376 12.678 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13299372 12.668 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chrX_-_135863502 12.662 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr14_+_24583905 12.607 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr16_+_55512801 12.587 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr16_-_4322695 12.540 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr16_-_86542463 12.477 LOC400550
uncharacterized LOC400550
chr18_-_500583 12.368 NM_130386
COLEC12
collectin sub-family member 12
chr9_-_94124149 12.355 AUH
AU RNA binding protein/enoyl-CoA hydratase
chr1_-_92351476 12.311 TGFBR3
transforming growth factor, beta receptor III
chr20_+_23015949 12.283 NM_001052
SSTR4
somatostatin receptor 4
chr6_+_64345726 12.218 PHF3
PHD finger protein 3
chr19_+_859673 12.196 CFD
complement factor D (adipsin)
chr15_-_44828864 12.176


chr2_-_71454200 12.165 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr11_+_13299349 12.047 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr7_-_95225802 12.004 NM_002612
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr3_-_114343052 11.934 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_72922513 11.907 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr6_+_64345709 11.858 PHF3
PHD finger protein 3
chr10_+_111969988 11.844 NM_001008541
MXI1
MAX interactor 1
chr19_+_1205773 11.711 NM_000455
STK11
serine/threonine kinase 11
chr1_-_182357871 11.709 GLUL
glutamate-ammonia ligase
chr16_-_1832304 11.579 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr2_+_132480063 11.529 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr13_-_36920396 11.523 SPG20
spastic paraplegia 20 (Troyer syndrome)
chr3_-_3221390 11.428 NM_001173482
NM_016302
CRBN

cereblon

chr6_+_64345672 11.409 PHF3
PHD finger protein 3
chr19_+_13875345 11.383 MRI1
methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr11_-_72504643 11.368 NM_006645
STARD10
StAR-related lipid transfer (START) domain containing 10
chr3_+_9691184 11.318 MTMR14
myotubularin related protein 14
chr3_-_3221361 11.311 CRBN
cereblon
chr3_-_3221385 11.278 CRBN
cereblon
chr17_-_42580745 11.099 GPATCH8
G patch domain containing 8
chr6_-_152623213 11.003 SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_154840460 10.981


chr17_-_40897025 10.973 NM_001991
EZH1
enhancer of zeste homolog 1 (Drosophila)
chr22_-_38902315 10.945 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr1_-_45956795 10.932 NM_007170
TESK2
testis-specific kinase 2
chr22_-_38902281 10.920 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr1_-_115053677 10.778 TRIM33
tripartite motif containing 33
chr14_-_21493122 10.775 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr5_+_176853673 10.747 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr5_-_146435589 10.695 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr3_+_46411632 10.618 NM_000579
NM_001100168
CCR5

chemokine (C-C motif) receptor 5

chr3_+_147127151 10.471 NM_003412
ZIC1
Zic family member 1
chr5_-_64920100 10.464 TRIM23
tripartite motif containing 23
chr3_-_48956817 10.397 NM_001123040
C3orf71
chromosome 3 open reading frame 71
chr1_+_209878135 10.363 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr9_+_88897112 10.305


chr10_+_51549552 10.264 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr20_+_48429375 10.213 SLC9A8
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr3_+_9691116 9.985 NM_001077525
NM_001077526
NM_022485
MTMR14


myotubularin related protein 14


chr12_-_49504337 9.980 LMBR1L
limb region 1 homolog (mouse)-like
chr22_-_38902300 9.963 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr11_+_10476665 9.955 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr6_+_134758840 9.812 LOC154092
uncharacterized LOC154092
chr6_-_33168369 9.805 NM_021976
RXRB
retinoid X receptor, beta
chr13_+_79980420 9.757 RBM26-AS1
RBM26 antisense RNA 1 (non-protein coding)
chr15_-_40600118 9.755 NM_004573
PLCB2
phospholipase C, beta 2
chr11_+_63606535 9.730 MARK2
MAP/microtubule affinity-regulating kinase 2
chr17_+_65373923 9.695 NM_012417
NM_181671
PITPNC1

phosphatidylinositol transfer protein, cytoplasmic 1

chr17_+_77751929 9.593 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr14_+_56585147 9.550 PELI2
pellino homolog 2 (Drosophila)
chr5_-_64920149 9.536 NM_001656
NM_033227
NM_033228
TRIM23


tripartite motif containing 23


chr1_-_182357757 9.430 GLUL
glutamate-ammonia ligase
chr7_-_115670774 9.371 TFEC
transcription factor EC
chr11_+_13299329 9.351 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr7_-_76829109 9.269 NM_006682
FGL2
fibrinogen-like 2
chr7_-_37393271 9.241 NM_001206482
ELMO1
engulfment and cell motility 1
chr3_+_9691198 9.240 MTMR14
myotubularin related protein 14
chr12_+_96588254 9.226 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr15_+_99191671 9.177 IGF1R
insulin-like growth factor 1 receptor
chr12_+_12764755 9.148 NM_001310
CREBL2
cAMP responsive element binding protein-like 2
chr16_-_68033355 9.109 NM_022355
DPEP2
dipeptidase 2
chr5_+_169064238 9.105 NM_004946
DOCK2
dedicator of cytokinesis 2
chr17_-_80656461 9.025 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr2_+_12856813 8.977 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr19_-_50316360 8.926 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr11_+_63606346 8.756 NM_001039469
NM_001163296
NM_001163297
NM_004954
MARK2



MAP/microtubule affinity-regulating kinase 2



chr8_+_22133079 8.687 NM_001135721
PIWIL2
piwi-like 2 (Drosophila)
chr7_+_65419441 8.673 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr6_+_111303240 8.663 NM_032194
RPF2
ribosome production factor 2 homolog (S. cerevisiae)
chr1_+_150122415 8.592 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr2_-_198175324 8.571 ANKRD44
ankyrin repeat domain 44
chr7_-_17979998 8.495 SNX13
sorting nexin 13
chr8_+_22132809 8.465 NM_018068
PIWIL2
piwi-like 2 (Drosophila)
chrX_-_15333726 8.456 NM_001201583
NM_080873
ASB11

ankyrin repeat and SOCS box containing 11

chr14_-_23288912 8.440 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_-_20306908 8.422 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr3_-_12941547 8.421 IQSEC1
IQ motif and Sec7 domain 1
chr15_-_60884615 8.405 NM_134262
RORA
RAR-related orphan receptor A
chr11_+_63606598 8.361 MARK2
MAP/microtubule affinity-regulating kinase 2
chr8_-_127570465 8.219 FAM84B
family with sequence similarity 84, member B
chr1_+_150122095 8.204 NM_016274
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr15_+_25230199 8.189 PAR5
Prader-Willi/Angelman syndrome-5
chr16_-_4323000 8.180 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr1_+_150122246 8.116 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr5_-_142065991 8.091 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr6_+_139094656 8.008 NM_015439
CCDC28A
coiled-coil domain containing 28A
chr11_-_66335958 7.975 NM_003793
CTSF
cathepsin F
chr11_-_114466397 7.945 FAM55D
family with sequence similarity 55, member D
chr6_-_87804773 7.889 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr19_-_38720312 7.766 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr10_-_90712510 7.761 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr14_+_56584854 7.676 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr12_-_48213567 7.657 NM_001098416
NM_015401
HDAC7

histone deacetylase 7

chr16_-_57318574 7.623 NM_015993
PLLP
plasmolipin
chr17_+_38219040 7.615 NM_001190918
NM_003250
NM_199334
THRA


thyroid hormone receptor, alpha


chr19_+_57752051 7.599 NM_001023563
NM_001145078
ZNF805

zinc finger protein 805


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 1.35e-07 GO:0065007 biological regulation
1.71 2.55e-07 GO:0048583 regulation of response to stimulus
1.27 1.17e-06 GO:0050789 regulation of biological process
1.67 6.41e-06 GO:0007166 cell surface receptor linked signaling pathway
1.42 1.13e-05 GO:0023052 signaling
1.26 2.52e-05 GO:0050794 regulation of cellular process
2.12 2.65e-05 GO:0009890 negative regulation of biosynthetic process
2.13 2.84e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.43 4.18e-05 GO:0007165 signal transduction
2.11 8.30e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.52 9.38e-05 GO:0048519 negative regulation of biological process
2.10 2.27e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.10 2.75e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.08 4.18e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.82 5.91e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.14 5.96e-04 GO:0051253 negative regulation of RNA metabolic process
2.14 7.66e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.84 8.93e-04 GO:0031324 negative regulation of cellular metabolic process
2.02 2.12e-03 GO:0010629 negative regulation of gene expression
2.28 2.32e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.48 2.42e-03 GO:0048523 negative regulation of cellular process
1.76 3.15e-03 GO:0009892 negative regulation of metabolic process
1.32 3.22e-03 GO:0051716 cellular response to stimulus
2.17 3.67e-03 GO:0050776 regulation of immune response
1.91 4.05e-03 GO:0002682 regulation of immune system process
1.41 4.62e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 7.24e-03 GO:0032501 multicellular organismal process
1.22 1.86e-02 GO:0050896 response to stimulus
1.72 1.98e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.37 2.67e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.51 2.69e-02 GO:0023051 regulation of signaling
1.37 3.24e-02 GO:0009889 regulation of biosynthetic process
1.84 3.86e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.37 4.00e-02 GO:0031326 regulation of cellular biosynthetic process
1.77 4.10e-02 GO:0006955 immune response

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.52 1.94e-02 GO:0005887 integral to plasma membrane
1.50 3.69e-02 GO:0031226 intrinsic to plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.10 6.40e-06 GO:0043565 sequence-specific DNA binding
1.85 1.81e-05 GO:0001071 nucleic acid binding transcription factor activity
1.85 1.81e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.72 7.77e-04 GO:0030528 transcription regulator activity
2.21 1.14e-02 GO:0016564 transcription repressor activity
4.48 1.22e-02 GO:0003707 steroid hormone receptor activity
2.16 1.92e-02 GO:0016563 transcription activator activity
2.47 2.13e-02 GO:0000975 regulatory region DNA binding
2.47 2.13e-02 GO:0001067 regulatory region nucleic acid binding
2.47 2.13e-02 GO:0044212 transcription regulatory region DNA binding
4.23 2.15e-02 GO:0004879 ligand-dependent nuclear receptor activity
2.46 3.15e-02 GO:0010843 promoter binding